is cytosine a purine - Grieving with Gout: How to Overcome the Arthritis Symptoms and the Pain
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Grieving with Gout: How to Overcome the Arthritis Symptoms and the Pain

Did you know that gout has often been labeled the most painful types of arthritis? Unfortunately, you or either someone you know suffers from gout. Perhaps, you are grieving with the disease that makes sleep and life miserable. Heat, Pain, Redness, Stiffness, Swelling, Arthritis attacks are a common event in the life of gout suffers. But it doesn't have to be this way? You can prevent gout attacks be making some simple lifestyle changes, lowering your uric acid levels and you can also cure gout attacks in minutes with even simpler gout home remedies! However, most of these home remedies are unknown by most sufferers.


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Devil's Claw is tolerated well by the vast majority of those treating their Gout by natural means, but be sure to talk with your doctor first - especially if you have ulcers, diabetes, high or low blood pressure, plant allergies, heart problems, are pregnant, could become pregnant or if you a nursing mother.

2. Take Vitamin C tablets! Vitamin C as well as fruit also lowers uric acid levels in the body thus preventing gout. 3. Apple cider vinegar - both ingested and applied to swollen area can help treat your symptoms. As a mixture you drink, it is thought that apple cider vinegar actually changes the pH of your blood which lowers uric acid levels.

In the world of natural gout remedies, uric acid's removal can be improved by making it more soluble. This is achieved by drinking lots of water and by raising body pH levels in various ways.

Extract of Devil's Claw root made its way to Europe in the early 1900s and was used to improve digestion and inflammation, but it is more widely used today as a natural Gout remedy and other joint ailments.

It has been having a decent degree of success. Elimination of gout attacks In its most recent statement the developing company's most significant remark was that the extension trial group receiving Pegloticase every two weeks, there were only four gout attacks among those who had been administered Pegloticase (8 mg) every fortnight for two months, in subsequent months. And none in this group had a gout attack after five months of Pegloticase treatment, in following months. All were patients who had been through a phase 3 trial.

Among fruits and green vegetables, a proper gout diet can also contain some meats (chicken and low-fat meats) and low-fat milk. Cereals are also good for gout. A proper gout diet should contain: fruits, tomatoes, broccoli, soy (soy replacements of certain dairy products like milk and cheese are strongly recommended), brown rice, cereals, and bread. Drinking plenty of water (around two liters each day) is also important for easing the symptoms of gout, helping the kidneys to eliminate the surplus of uric acid.

31% of patients who had not reduced tophi at the end of these phase 3 trials did show tophi reduction in the extension trial. It would seem that the longer a gout sufferer is able to take Pegloticase the more successful it may be, in tophi cases at least.

For natural therapy of Gout and other Musculoskeletal disorders in tablet form, Devil's Claw is recommended for adults 18 and older only. For dosing, read the label information on the bottle to determine the amount of Harpagoside formulated and adjust your dose to be equivalent to 50-100 mg, taking it two or three times a day.

The chemical, principle extracted from the Devil's Claw root, (Harpagoside procumbens) is a Glycoside (sugar derivative) called Harpagoside. This active ingredient contributes the natural anti-inflammatory properties used as a Gout remedy and other painful disorders of the Musculoskeletal system.

Higher doses can be taken during the painful acute phase of Gout. Natural remedy such as Devil's Claw can be taken otherwise, i.e., if your beverage of choice is tea, add one teaspoon of dried root of Devil's Claw in 2 cups of boiling water and steep for 20 minutes before straining it then allow it to cool.

A proper gout diet and a healthy lifestyle are the best means of preventing and easing the symptoms of gout. It is a fact that there is no specific cure for gout and the treatment often prescribed for the disease usually acts by controlling pain attacks and inflammation. There is little that medicines can do for the patients who suffer from gout, especially for those who have chronic forms of the disease. Proper gout diet can both ease the symptoms of gout and prevent injury and complications. It is known to be the best way of handling the effects of the disease.

While experts have not been able to isolate the exact mechanism of action of Devil's Claw, numerous studies have been conducted with documented success in pain relief of Gout and other ailments. Several of those studies compared Devil's Claw root extract to Cox-2 inhibitors such as Vioxx?? in clinical trials. They concluded that the natural supplement appeared to work in the same manner as non-steroidal anti-inflammatory medications (NSAIDS).

Gout is a metabolic disorder created when uric acid, which is normally excreted from the body in the urine, fails to metabolize properly and builds up in the blood stream. As it spills into the blood system, crystals are formed that collect in a joint and its surrounding tissues causing intense pain and severe inflammation.

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Joe Barton writes for Barton Publishing Inc., a natural health company specializing in educating people of safe, affordable natural remedies. To see how you can naturally treat your gout in minutes... guaranteed! Click here: Cure Your Gout Website

You can enjoy the tea 2 or 3 times a day as Gout's natural remedy or to improve indigestion and loss of appetite. As with any medicinal substances you chose to consume, it is important to first consult with your health care provider for help coordinating the use of various natural supplements - especially in conjunction with traditional medications.

But, I need immediate relief? You can also naturally have immediate relief for your gout attacks in hours. Believe it or not, you can be relieved of gout pain in hours if you take specific foods (at every grocery store) whenever your gout attacks occur. Imagine, being able to fall back to sleep and NOT being awake the rest of the night. Learn how thousands are naturally treating their gout and learning how to take back their life from gout's symptoms. And finally, I want to urge you to consider a guaranteed natural remedy with no side-effects instead of the traditional medicinal approaches which carry numerous negative side effects. Besides having immediate relief, you will save hundreds from over-priced prescriptions and the hundred dollar hospital visit. Besides, with a 100% no-questions asked guarantee, what else could be stopping you? Please take some time to check out our website.

In May 2008 the U.S. based company developing Pegloticase made another upbeat statement assessment of what they have learnt in its Phase 3 and open label extension trials. Note that Pegloticase still awaits approval from medical authorities so I am writing here about a new gout drug that is still under development.

TRIAL SUCCESS WITH DIFFICULT TO TREAT GOUT PATIENTS Pegloticase is significant because its trials have focused on gout patients who have not had success with other gout drugs, or who have medical conditions which prohibit the use of them. Thus it has been tackling harder-to-treat gout cases, not the easier ones. Hard to treat cases are a significant percentage of the gout sufferer universe.

Proper gout diet replaces the foods that are considered to cause gout due to their high levels of purine with healthy, better tolerated foods. Foods that are rich in saturated fats should also be avoided.

Pegloticase's answer to the excess uric acid level problem is to remove it by ingeniously converting uric acid into something else, a substance called Allantoin. Allantoin is more soluble and better excreted than uric acid. The principle comes from the way most animals do it. They do it by converting UA to Allantoin, but this is something humans cannot do naturally. Hence the formulation of Pegloticase.

 
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SIDE EFFECTS Of course Pegloticase has caused side effects, in the extension trial in about 1 in 5 patients. The developing company has said that most were mild, moderate, or controllable. But in some cases more severe side effects have been described as including chest and back pains, muscle cramps, sweating and flushes.

In order to understand how the herb Devil's Claw can be effective as a natural Gout remedy, let's discuss the definition of Gout and how it presents itself in the body.

Other encouraging statements were that all extension trial patients who had responded earlier to treatment and who were on the every two week course maintained normal uric acid levels, (some were new joiners). 70% of those on an every four week course who had responded earlier to treatment, maintained normal uric acid levels.

HOW PEGLOTICASE WORKS What makes Pegloticase a very interesting, and more importantly, a hopeful new gout drug, is the way it works. All drugs used in gout try to cure or alleviate the disease by reducing the body's uric acid (UA) levels. They do this by either inhibiting its production or making it easier to remove.

The foods that are known to have high levels of purine are meats like pork, beef, lamb, poultry, organ meats (brain, kidneys, liver and heart), fish and seafood (sardines, mackerel, oysters, caviar, calamari and crabs) and fat dairy products such as cheese, milk and butter. Even some vegetables like spinach, beans and peas are known to conatin large amounts of purines. However, green vegetables are thought to have no malign effects to the body. Fruits not only have low levels of purines, (and they are strongly recommended in any gout diet) but they also contain vitamins and minerals that are vital in the proper functioning of the body. Vitamin C, contained by most fruits, is a powerful natural anti-oxidant which helps in easing the symptoms of gout.

Though Devil's Claw a well-known Gout Remedy is used most commonly for natural treatment of the pain and inflammation of Gout, Rheumatoid Arthritis and muscle pain, it is also used for complaints related to stomach and gall bladder.

Also referred to as "the disease of kings", the occurrence and development of gout are strongly determined by improper diet. In the past, the disease predominantly affected nobles and royalty, due to their access to an abundance of foods that are known today to have high risks of causing gout. These days, many people are still confronted with gout, as they consume foods that interfere in the normal activity of the body. Mostly people living in developed societies are the ones who tend to be affected by gout. The consumption of some exotic foods like seafood (oysters, caviar, calamari, sushi) or improper diets that contain a lot of meats (pork, poultry, beef) are the factors that seem to facilitate the occurrence and the development of the disease. Statistics indicate that people who live in less-developed countries have a smaller chance of developing gout. Also, research results reveal the preponderance of obese people among those who are suffering from different forms of gout.

Pegloticase is getting closer to an application for approval by the U.S. FDA. Its developers hope to apply for a Biologics Licence Application in September 2008, and begin marketing it in 2009.

May was a good month for gout sufferers. Febuxostat, (EU trade/brand name Adenuric), the first new major drug medication for gout in over 40 years, was approved for marketing in member countries of the European Union.

Gout is a type of rheumatoid arthritis that causes pain and inflammation of the joints. The joints of the lower body seem to be affected the most. People with gout experience discomfort, swelling, local irritation and redness, itching sensations, pain, sometimes feeling a sensation of cold around the affected areas, the skin in those regions often looking stretched. Gout can also affect skin and soft tissue such as muscles and tendons, making them less flexible. Gout is known to be caused mainly by the presence in excess of crystallized uric acid deposits inside the body, which are difficultly eliminated by the kidneys. Improper diet can lead to more accumulation of uric acid in the body, as some foods that contain high levels of purine are synthesized by the body into uric acid.

Since thousands of years ago, the natives of south and southeastern Africa have known a little something about medicinally treating inflammation. Named for the appearance of the fruit of its root, Devil's Claw (also referred to as Cat's Claw) is recognized by its hook-like protrusions on pods of the plant.

Some reports of ringing in the ears and upset stomach have been associated with taking Devil's Claw. Weigh your treatment options with natural supplementation carefully and use these tools to treat your Gout with natural remedies and avoid that painful flare-up!

5. Take a hike! Literally, go for a walk or a hike to get some exercise. You would be surprised how much better you will about yourself and your body! And you will also shed some extra pounds.

In other patient groups there were reductions in attacks and improvement in tophi reduction. Tophi are those knobbly shaped, awkward looking, lumps of MSU crystals that often develop in longer term gout sufferers.

Devil's Claw is available for consumption in various forms. The English began brewing it as a bitter tasting tea, which may still hold true that if it tastes bad, it must be good for you! Drinking Devil's Claw as tea remains an option but more commonly today, this Arthritis and Gout remedy is available in oral formulated tablets or capsules, liquid tinctures, as well as a topical ointment for skin irritations.

Betty Roberts is the author of Gout-Info.com, a website dedicated to Gout sufferers.

Serious potential interactions between the ingredients exist, and there are those among us that should steer clear as some substances can be potentially harmful to our health and well-being.

4. Maintain Healthy Weight! Every pound you shed gives you a better chance of leaving gout in the dust. Begin eating healthier with fruits, veggies, fresh foods, whole grains and low fat foods.

Simple Gout Prevention by Lowering Uric Acid Levels 1. Water has been known to be beneficial to almost every ailment, including gout. Drink 10-12 glasses of water each day will prevent uric acid crystals from forming and thus prevent gout!

The consistent use of Devil's Claw may reduce the need for other NSAIDS and allow a person suffering from Gout to take lower doses of pain and anti-inflammatory medications, and possibly omit them in the future.

This suggests that progression of the disease may be contained in difficult-to-treat cases, and therefore may not cause other medical conditions such as kidney stones heart disease and hypertension.

Further discussion needs to occur if you are on medications to treat any of the above ailments or conditions. This is crucial if you are being treated medically for diabetes, heart ailments or taking blood thinners.

Gout may also be called metabolic arthritis referring to the dysfunctional metabolism of uric acid. The trick is to reduce uric acid levels and combat painful inflammation. Gout's natural remedies and treatments have emerged with Devil's Claw among the top of the heap.

NB. The contents of this article contain medical information not medical advice. Please always discuss gout remedies with your doctor or other health care professional, before implementing any treatment.


 
 
     
 
 





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