gout medication - A New Gout Drug. Febuxostat wins marketing approval in the European Union
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A New Gout Drug. Febuxostat wins marketing approval in the European Union

It has taken a very long time for a major new gout drug to be developed and approved. Probably the best gout news in over 40 years, is that Febuxostat, which has been given the trade/brand name of Adenuric, has been approved by the European Medicines Agency for marketing in European Union (EU) countries.


WHO WILL BE PRESCRIBED IT? The recommended dose is one 80 mg daily tablet. If after two weeks there is no reduction in UA levels, your doctor may increase the dose to 120 mg daily. Patients will need another serum UA test after two weeks treatment to find out how well it's doing. In trials it has usually worked quickly, within a couple of weeks.


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  IT'S NOT PERFECT In trials its success rate in reducing UA levels down to the important 6.0 mg/dL (357 mmol/??mol) level was not 100%. About 35% of trial patients did not achieve the target. This may have been partly because so many gout sufferers are not UA over-producers, the problem Febuxostat addresses, but under-excretors of uric acid.

A gout is a type of arthritis, which is the inflammation of your joints. In got cases, the attacks cause severe pain, sewlling and redness. These gout attack symptoms happen very sudden, without any further warning. To heal a gout case is impossible, because their exists no cure. However, there are things that can be done to control and treat your gout case.

To control and treat a gout takes more than medication. A diet and probably a change in your lifestyle must also be made if suffering from a gout. The medication that you will be prescribed to treat your gout case depend on some factors. Your doctor will give you the proper gout treatment after taking into consideration your age, state of health, other medication that you take and last but not least the severity of your gout attacks. The main drugs that you will be given are anti- inflammatory medicine:

To prevent future attacks, your doctor can prescribe a medicine to reduce uric acid buildup in your blood. Changing the way you eat can help you conduct your gout. Eat a healthy mix of foods so you get the nutrients you need. Limit foods like meat, fish, and beer. Drink plenty of water and other fluids.Life style changes such as limiting alcohol consumption, and limiting meals with meats and fish rich in purines can also be helpful in controlling gout. Weight loss may be very important this condition. You should also avoid certain animal proteins, such as: seafood; liver; kidney; heart; gizzard; sweetbreads; meat extracts; and gravy.

Though these synthetic medications do help with the pain or inflammation, all of these treatments don't do anything to cure the cause of gout, high uric acid levels.

Approval in one country does not mean approval in another, but the fact that the European Medicines Agency has approved it will carry weight when the medical authorities in other countries consider its approval.

5. Your Diet- Possibly the best remedy, your diet can literally change how you look to how you feel. It also can determine whether you ever have a gout attack again. Our Gout Remedy Report gives a detailed list of foods you should eat and foods you should pass on.

Tophi If you have tophi, it's heartening to know that Febuxostat has been shown to have success against tophi. Measured tophi areas reduced in many patients with tophi. The presence of tophi will be an additional factor in favour of a decision to prescribe Febuxostat (Adenuric).

Alcohol and certain foods can trigger a gout attack. Events such as strokes, heart attacks or surgery may also cause gout. Gout is strongly associated with obesity, hypertension, hyperlipidemia and diabetes. Because of genetic factors, gout tends to run in some families. A variety of treatments can help you manage your gout. Traditionally treatment for acute gout has consisted of colchicine , which can be effective if given early in the attack. Gout often is treated with nonsteroidal anti-inflammatories (NSAIDs) such as naproxen (e.g., Anaprox, Naprosyn) and indomethacin (e.g., Indocin), usually for 3-7 days.

Does this sound like you? It is the middle of the night and you suddenly wince with pain. Of all things, your big toe is throbbing and feels like it is on fire. As you hobble to turn on the lights, you see that your toe is swollen, reddened and the pain is beyond bearable.

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Generally, Febuxostat has been more effective when UA levels are below 10.0 mg/dL (595 mmol/??mol). However, even if they have been above this level, it has reduced UA levels down to the target in about 40% of study patients at an 80 mg dosage, and by more at higher dosages.

Is a natural treatment for gout really worth trying? If you consider yourself a person who wants to better their health, then you are the perfect candidate to cure gout with no medication.

Do you suffer from the arthritic pain of gout? Have you been taking medication with little to no relief? Are you tired of popping pills to hide the pain?

The list of high purine food is actually quite long thus it is very important for gout patients to be wary of the food they consume daily. Some of the common beverages, which gout patients should avoid, include coffee, tea, cocoa and even chocolate. Some of these beverages are already part and parcel of ones daily life that it is seriously a bit different to imagine having to abstain drinking them. If you think it is really no big deal to indulge in it once in awhile, you will really have to think twice. Is the pain from a possible gout attack really going to be worth it from your indulgence?

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You will not need to be on a low purine diet, and more good news is that it can be prescribed for the elderly. Kidney and liver disease In trials it has performed quite well with patients who have mild kidney disease. 44% of patients achieved the target at an 80 mg dosage, more at higher dosages. Better results than Allopurinol. If you have mild kidney disease (renal impairment) or mild liver problems (hepatic impairment) your doctor will judge whether Adenuric/Febuxostat can be taken safely.

And knowing the cause of gout (overweight, alcohol consumption, your diet), modern day researchers now know the cure for gout. And surprisingly it is NOT synthetic medications.

The second list of food gout patients should avoid includes gizzard, kidney, seafood, heart, gravy and red meats. Alcohol should also be place in the list of food to be avoided. Any form of alcohol including wine or beer can trigger attacks of gout. It is significant to memorize the list of food to avoid as it can help to reduce the amount of gout attacks controlling drugs one will have to take.

1. Water Therapy- If you are going to be the healthy person you want to be, you must start drinking 10-12 glasses of water a day. Water is a natural flusher that works to flush the potent uric levels out of the blood stream. It will also eliminate the feeling of 'being hungry'.

3. Berries- Did you know that there is various berries that will provide instant relief during a gout attack. For instance, because of their ability to efficiently neutralize uric acid, strawberries can create immediate relief from your symptoms. Suggested serving size: 1 cup during an attack.

At 120 mg it has reduced UA levels to the target of 6.0 mg/dL in over 60% of study patients. At 80 mg the numbers were around 51%. Allopurinol at a 300 mg dosage in most participants achieved this is 22% of study patients. Hence the excited buzz in rheumatology circles since these kinds of results became apparent in its trials. At or below 6.0 mg/dL gout is more likely to be cured or managed better.

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You can cure it with a natural treatment for gout based on your lifestyle. Natural Health Gout Tips

The treatment includes medicines like allopurinol, which decrease the level of uric acid, or there are other medicines like colchicine, which decrease inflammation. Also there are medicines called uricosuric agents that increase the removal of uric acid in urine. Colchicine works best if taken really early in the attack and sometimes repeat does may need to be taken periodically such as every two hours or so till there is pain relief or a maximum dose is reached or there are side effects like gastrointestinal upset.

Gout is the cause of uric acid in the body which is a by-product of a very necessary part of your body's normal function. In the case of gout, the body is unable to break down the high levels of the uric acid. The uric acid eventually develops into crystals which take up residency in your joints. The most typical joint affected is the toe. However, other gout joints affected include: the feet, the ankles, the wrists, fingers and elbows. If you or a loved one suffers from gout, you can neutralize the uric acid and eliminate the pain in hours.

 
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- corticosteroids are the alternative for a gout patient who can not use the nonsteroidal drugs; these as well reduce the inflammation caused by the gout in no more than a few hours; you can find this type of gout drug in form of pills or injections;

People always have the mentality that as long as one does not eat junk food, one can be considered to have a healthy diet. Actually a diet that is considered healthy to one might be unhealthy to another person, it can be quite subjective in this context. Gout patients are usually advice to go on a special diet, which will help to alleviate the pain cause by gout attacks. This diet will require one to avoid food that will increase the uric acid in the body. The list of food to avoid will also include certain food, which are considered healthy by most standards and definitions.

With this said, you should immediately find a treatment that best works with your body. Most doctors prescribe an arrangement of anti-inflammatory and pain relievers including Non-steroidal anti-inflammatory drugs (NSAIDs), Corticosteroids, or Colchicines.

It is seriously important for people with gout to bear in mind the types of food items that are harmful and beneficial to their gout conditions. Since you now have a better knowledge of the food types that should be consumed, it might be a good habit of what to buy and what not to buy when you do your grocery shopping the next time.

And it may cause side effects of course. See the bottom of this article. Febuxostat (Adenuric) is not unfortunately a treatment for gout pain. It won't be used instead of NSAIDS like Indomethacin, Colchicine, and corticosteroids.

This approval applies only to EU countries. Febuxostat has not yet been approved in the United States. If you are reading this from a non-EU country, or the US, you can check with your doctor to find out whether, or when, Febuxostat will be approved in your country.

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Your uric acid levels will have to be high. If you have gout but normal or slightly raised uric acid levels as some do, it is unlikely to be prescribed.

3. Apple cider vinegar can help treat gout by being consumed or applied to swollen area. As a drink, you can actually add the vinegar to a cup of tea to change the pH of your blood which lowers the uric acid levels.

Gout is one of the most common forms of arthritis (joint inflammation). Gout is condition that results from crystals of uric acid depositing in tissues of the body. Gout usually affects the first metatarsal phalangeal joint of the big toe (hallux) or the ankle joints. Gout most often affects the big toe but can also affect the ankle, knee, foot, hand, wrist and elbow. Approximately one million people in the United States suffer from attacks of gout. Gout is nine times more common in men than in women. It predominantly attacks males after puberty, with a peak age of 75. In women, gout attacks usually occur after menopause.

4. Begin eating healthier with fruits, veggies, fresh foods, whole grains and low fat foods. 5. Take a hike! Literally, go for a walk or a hike to get some exercise. After the area loosens up, your body will thank you and you will naturally lower the uric acid levels in your blood.

And it won't cost $1,000+! In fact, the cost could be as low as $20 for the store-boughten ingredients that neutralize the uric acid causing the pain.

John Mepham has lost track of the number of hours he has spent researching gout treatments. His best tip for curing gout naturally? Get to your ideal weight whatever the sacrifices may be. Learn more about natural gout treatment at www.gout-smashers-guide.com It's an e-book with an emphasis on natural gout treatment

Skyjoe is a well-known author, website publisher and owner of http://www.mygeneralknowledge.com. ??Skyjoe. All rights reserved. This article may be freely distributed as long as it remains unaltered inclusive of the active links and the copyright notice. No alteration is allowed without express written permission from the author.

The specific dose and the manner of taking these medicines are best discussed with your healthcare provider. Common side effects of these drugs include stomach upset and ulcers from prednisone and ibuprofen type of medications, diarrhea from colchicine and sometimes gout can get worse from allopurinol especially if the person is not on colchicine first during an acute attack.

2. Vitamin C! Vitamin C has been documented to lower uric acid levels in the body as well as help the body's immunity. Do not exceed 2,000 mg of Vitamin C per day.

It occurs more frequently in countries that have a high standard of living. The most common sign of gout is a nighttime attack of swelling, tenderness, redness, and sharp pain in your big toe. There may also be the feeling that the skin around the area is stretching or tearing. There seem to be a number of factors that can cause people to develop gout. Some medications can prevent uric acid from leaving the body. Cyclosporine which is a medication used to suppress the body's immune system and prevent rejection after organ transplant, also increases the risk for developing gout. This can cause a build up of uric acid crystals.

BENEFITS In large trials Febuxostat (Adenuric) has outperformed Allopurinol, the most common gout medication for long term treatment. Like Allopurinol, it works to lower uric acid production by inhibiting xanthine oxidase, an enzyme required to produce uric acid. In two major studies it reduced uric acid (UA) in more gout sufferers, and more patients reached the target 6.0 mg/dL level more quickly, than did those on Allopurinol.

It is recommended that NSAIDs or Colchicine are used along with Adenuric. This is because, as with Allopurinol, on a course of Febuxostat, there may be an initial increase in gout flares. If this happens you must battle through the attacks and continue taking Adenuric.

Most of the time the symptom can be controlled by anti-inflammatory medications like naproxen or indomethacin. In severe cases steroids like prednisone may be needed. Some people even need injections into the joints. Fluid from the swollen joints can be removed and analyzed for the uric acid crystals.

"My husband (who suffered from gout) has seen several doctors in the past year. And recently a doctor said that he could give him an injection that would cost $1,500. We refused and bought your Cure Gout Naturally Remedy Report. My husband has been gout free for 2 months and you saved us two weeks salary. Thanks!" ~ Barb, CA

NB. The contents of this article contain medical information not medical advice. Please always discuss remedies with your doctor or other health care professional, before implementing any treatment.

Gout, which is a common form of arthritis especially among man of age 40 to 50, is caused by the deposits of excess uric acid in the bloodstream on the joint connections area. By avoiding food that will cause the body to generate more uric acid than necessary in the body is very critical. Food items containing high purine level is found to increase the production of uric acid in the human body. It is essential for people with gout to avoid such food completely.

Even though choosing the correct food to consume is important for people with gout, drinking plenty of water is also essential. Drinking lots of water will help the body to remove the excessive uric acid in the body through the urinal system. Exercising regularly will also help gout patients to improve their overall gout conditions.

- another drug used to calm down the gout flare symptoms is colchicine; its effect can been seen in a few hours time; Besides these drugs that are used to reduce the symptoms of a gout flare, there are also other drugs for preventing the gout attacks from happening. Allopurinol or probenecid lower the levels of uric acid that you have in your blood, thus reducing the risk of another gout attack. They are only given to the gout patients that suffer from many gout flares or have kidney stones because of the uric acid. However, if the levels of uric acid are lowered too sudden, this may trigger a gout attack as well. To prevent this from happening, doctors also prescribe colchicine to gout patients who take drugs to lower the levels of acid. Furthermore, the therapy with acid- lowering drugs is not started when the patient is suffering from a gout attack.

I am writing this feeling appalled! One of my ex-gout customers wrote a recent e-mail to me stating the cost of gout medication. I was completely unaware of the extreme expense of gout medication. I guess, I just assumed that mediation couldn't be more than a few hundred dollars. However, I was wrong!


Herbal remedies for gout have become very popular in recent years. There is very little evidence right now that shows alternative therapies are effective for gout. Uricinex is a breakthrough herbal product that we have recently discovered. Blueberries are high in anti-inflammatory compounds called anthocyanins, which help ease the pain of gout. Other herbal treatments that have shown some success include vitamin C - Taking supplemental amounts of vitamin C helps some people to reduce the uric acid in their blood. Taking 2-3 teaspoons of black cherry juice a day helps some people. Cherries are a popular home remedy for gout.


 
 
     
 
 





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