Purines - Symptoms of Gout and its Causes
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Symptoms of Gout and its Causes

Gout is also known as crystal-induced arthritis. It is a medical condition that sets in when uric acid crystals collect on the joints. At the first stage, gout usually affects the large joints in the big toe. Gradually it can spread to other parts of the body, like the ankles, the instep, the heels and the knees, the wrists and fingers of the hand and the elbows. In severe cases, even the shoulders, hips or spine can be affected. Gout does not spread from one joint to the next. Uric acid is a metabolic end product that is formed at the time the body breaks down purines present in certain food items. In normal conditions, the uric acid gets dissolved in the blood and gets eliminated from the body through the kidneys into the urine. However, people having a propensity for gout have such high levels of uric acid in their blood that the acid precipitates out in the form of crystals. The crystals get accumulated on the joints and other tissues, leading to inflammation and excruciating pain. A chronic condition can lead to the formation of tophi lumps formed under the skin due to large deposits on severely affected joints of the elbow, fingers and toes, and even on the external pinna.


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  Another medical condition, referred to as the pseudo-gout, results from the deposits of calcium-based crystals in the joints.

In almost 90 percent of incidences of gout, men over the age of 40 and menopausal women are affected. An "episode" often takes place during the night. Within 12 to 24 hours of the onset, the afflicted joint becomes severely inflamed and starts to ache rigorously. The gout attack usually lasts about five to 10 days.

The Signs and Symptoms of Gout include:

Hyperuricemia

Presence of uric acid crystals in joint fluid

More than one attack of acute arthritis

Arthritis that develops in 1 day

Attack of arthritis in only one joint, usually the toe, ankle, or knee

A painful joint that is swollen, red, and warm

The probable causes of gout include:

 
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Genetic defects in metabolism resulting in hyper-production and retention of uric acid in the blood

Kidney failure leading to hampered elimination of uric acid from the body

Diuretic medications employed in the treatment of heart failure and diabetes.

Erratic lifestyle, alcohol abuse, purine-rich diet and excess weight

Surgery or sudden injury, severe illness

Proper understanding of the cause and symptoms of gout can help in achieving a successful cure for gout attacks. Want to learn more about Gout Symptom Sign?, feel free to visit us at: http://www.about-goat.info/Articles/Gout_Symptoms.php

 
 
     
 
 





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Gout is a type of arthritis caused by the excessive accumulation of uric acid inside the organism. In large amounts, uric acid forms crystals which deposit in various regions of the body, causing inflammation, pain and swelling of the joints. Uric acid is a waste product that results from purine metabolism. Although most cases of gout are hereditary, occurring due to genetically acquired renal...


Foods that cause gout are rich in a chemical called purines. These foods include organ meats such as liver, brain, kidneys and sweetbreads. Other foods include anchovies, herring, dried peas and beans. The purines get converted to uric acid but if they accumulate in excess they will cause gout. The uric acid crystals, which form will irritate the lining of joints such as the one in the big...


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